Paul Y Takahashi,1,2 Euijung Ryu,3 Janet E Olson,3 Erin M Winkler,4 Matthew A Hathcock,3 Ruchi Gupta,3 Jeff A Sloan,3 Jyotishman Pathak,3 Suzette J Bielinski,3 James R Cerhan3 1Division of Primary Care Internal Medicine, 2Department of Internal Medicine, 3Department of Health Sciences Research, 4Center for Individualized Medicine, Mayo Clinic, Roch
Group A streptococcus (GAS) is a versatile pathogen that causes a wide spectrum of diseases in humans.Invading host cells is a known strategy for GAS to avoid antibiotic killing and immune recognition.However, the underlying mechanisms of GAS resistance to intracellular killing need to be explored.Endothelial HMEC-1 cells were infected with GAS, me
The alarming growth of multi-drug resistant bacteria has led to a quest for alternative antibacterial therapeutics.One strategy to circumvent the already existing resistance is the use of photodynamic therapy.Antimicrobial photodynamic therapy (aPDT) involves the use of non-toxic photosensitizers in combination with light and in situ oxygen to gene